BULLETIN OF THE VETERINARY INSTITUTE IN PULAWY, vol.52, no.1, pp.131-134, 2008 (SCI-Expanded)
The pathomorphological and immunohistochemical features of cholangiocarcinoma in an 11-year-old female Van cat were described. At necropsy, the primary tumour was determined in the liver. The tumour was greyish-white, firm, and multinodular. The size of these nodules ranged between 1 cm and 3 cm. There were metastases in the mesentery, portal lymph nodes, peritoneum, and lung. Immunohistochemically, the tumour cells showed positive immunoreactivity for S100 and cytokeratin, and negative for a-fetoprotein. According to morphological and immunohistochemical findings, this tumour was defined as a cholangiocarcinoma.