Secondary Lymphoma in a Patient with a History of Unilateral Retinoblastoma


KOZANOGLU B., SEZGİN G. , BAGIR E., ÖZKAN A., BAYRAM İ. , TANYELİ A., ...Daha Fazla

CUKUROVA MEDICAL JOURNAL, cilt.40, ss.33-37, 2015 (ESCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 40
  • Basım Tarihi: 2015
  • Dergi Adı: CUKUROVA MEDICAL JOURNAL
  • Sayfa Sayıları: ss.33-37

Özet

Second malignancies develop with increased incidence in patients with herediter retinoblastoma. The most common second malignancies in retinoblastoma survivors are soft tissue sarcoma and osteosarcoma. Lymphoma developing as a second malignancy has rarely been reported. Here we report a case of lymphoma diagnosed in a 13 year-old-boy, 12 years after the diagnosis of unilateral retinoblastoma having heterozygous p.R552 (c.1654C>T) mutation, treated with enucleation and radiotherapy. The risk of second tumour is higher in the hereditary retinoblastoma, especially in cases undergoing external beam radiation therapy.