Evaluation of single nucleotide polymorphisms of angiotensin II type 2 receptor (AGTR2) gene and interleukin 4 (IL-4) gene for their contribution to the risk of preeclampsia in Turkish population

ÖZPAK L., PAZARBAŞI A., Keser N., Yilmaz M. B., LÜLEYAP H. Ü., Ozgunen F. T.

CUKUROVA MEDICAL JOURNAL, vol.42, no.3, pp.477-483, 2017 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 42 Issue: 3
  • Publication Date: 2017
  • Doi Number: 10.17826/cutf.297910
  • Journal Name: CUKUROVA MEDICAL JOURNAL
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.477-483
  • Çukurova University Affiliated: Yes

Abstract

Purpose: Preeclampsia, specific to human pregnancies, is a serious disorder, which occurs approximately in 6-10% of all pregnancies. It is a complex disorder, in which immune and genetic factors also take part. The aim of the current study was toinvestigate whether there is an association between AGTR2 A1675G and IL4 -590 (C>T) polymorphisms and preeclampsia.