Evaluation of combined therapeutic effects of hydrogen sulfide donor sodium hydrogen sulfide and phosphodiesterase type-5 inhibitor tadalafil on erectile dysfunction in a partially bladder outlet obstructed rat model

Yılmaz Oral, DİDEM; Kaya-Sezginer, Ecem; Oztekin, Cetin; Bayatli, Nur; Lokman, Utku; Gur, Serap

doi:10.1002/nau.24333

Evaluation of combined therapeutic effects of hydrogen sulfide donor sodium hydrogen sulfide and phosphodiesterase type-5 inhibitor tadalafil on erectile dysfunction in a partially bladder outlet obstructed rat model

Yılmaz Oral D., Kaya-Sezginer E., Oztekin C. V., Bayatli N., Lokman U., Gur S.

NEUROUROLOGY AND URODYNAMICS, cilt.39, ss.1087-1097, 2020 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 39
Basım Tarihi: 2020
Doi Numarası: 10.1002/nau.24333
Dergi Adı: NEUROUROLOGY AND URODYNAMICS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE, MEDLINE
Sayfa Sayıları: ss.1087-1097
Anahtar Kelimeler: benign prostatic hyperplasia, erectile dysfunction, hydrogen sulfide, partial bladder outlet obstruction, tadalafil, NITRIC-OXIDE, PATHWAY
Çukurova Üniversitesi Adresli: Evet

Özet

Aims To evaluate the impacts of hydrogen sulfide (H2S) donor, sodium hydrogen sulfide (NaHS), and phosphodiesterase type-5 inhibitor (PDE5i), tadalafil per se and their combination treatment on partial bladder outlet obstruction (PBOO)-induced erectile dysfunction (ED).