Evaluation of Forkhead Box P3 gene polymorphisms in chronic HBV infection


Akgollu E.

JOURNAL OF GENE MEDICINE, cilt.22, sa.6, 2020 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 22 Konu: 6
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1002/jgm.3172
  • Dergi Adı: JOURNAL OF GENE MEDICINE

Özet

Background Hepatitis B virus (HBV) infection causes liver failure, liver cirrhosis and hepatocellular carcinoma. The FOXP3 gene polymorphisms, the rs2232365 A/G and the rs3761548 A/C, were identified to be associated with regulatory T cell-mediated immunosuppression. The response to HBV infection may be affected by FOXP3 polymorphisms. The present study aimed to assess the relationship between FOXP3 gene polymorphisms and chronic HBV infection risk.