Correlation of clinical phenotype with a pericentric inversion of chromosome 9 and genetic counseling


DEMİRHAN O. , PAZARBAŞI A. , Suleymanova-Karahan D., Tanriverdi N., KILINÇ Y.

SAUDI MEDICAL JOURNAL, cilt.29, ss.946-951, 2008 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 29 Konu: 7
  • Basım Tarihi: 2008
  • Dergi Adı: SAUDI MEDICAL JOURNAL
  • Sayfa Sayıları: ss.946-951

Özet

Objectives: To describe the history of 157 carriers of pericentric inversions on chromosome 9 [inv(9)] with karyotype analyses and evaluate the significance of these findings. Methods: We studied the incidence, clinical significance, and genetic counseling of inv(9) (p11;q12), (p11;q13), and (p11;q21) patients who were referred to our laboratory from various clinics of the Medical Faculty, Cukurova University, Adana, Turkey retrospectively from 157 cases of 15528 cytogenetic analyses collected between May 1993 and February 2007.