Prognostic significance of EBV-LMP1 and VEGF-A expressions in non-Hodgkin's lymphomas


PAYDAŞ S. , ERGİN M. , ERDOĞAN Ş. , SEYDAOĞLU G.

LEUKEMIA RESEARCH, cilt.32, sa.9, ss.1424-1430, 2008 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 32 Konu: 9
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.leukres.2008.01.008
  • Dergi Adı: LEUKEMIA RESEARCH
  • Sayfa Sayıları: ss.1424-1430

Özet

Background and aim: EBV is an important virus in the pathogenesis of NHL. VEGF-A is the essential factor in tumor angiogenesis. There is evidence of cross talk between angiogenesis and viral carcinogenesis. The viral latent protein LMP1, may play a role by inducing expression of angiogenic factors In this study EBV-LMP1 and VEGF-A expressions have been studied in cases with NHL and prognostic significance of these has been evaluated.