Prevalence of HLA-DQ02 and HLA-DQ08 in Patients with Celiac Disease in Eastern Anatolia and the Diagnostic Role of HLA-DQ02 and HLA-DQ08 Genotyping

BALKAN E., İŞLEK A., YAŞAR E., DOĞAN H.

Turkish Journal of Immunology, vol.7, no.1, pp.6-10, 2019 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 1
  • Publication Date: 2019
  • Doi Number: 10.25002/tji.2019.862
  • Journal Name: Turkish Journal of Immunology
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.6-10
  • Çukurova University Affiliated: No

Abstract

Introducton: Celiac disease (CD) is diagnosed with serological rests and small bowel biopsy. There is a strong link between CD and human leukocyte antigens (HLA). In this study, we aimed to determine the role of HLA alleles DQ*02 and DQ*08 in the diagnosis of pediatric CD patients and to determine the prevalence of these alleles in the population.