The effects of valproic acid and carbamazepine on strength-duration properties of peripheral nerve


Yerdelen D., Koc F.

NEUROSCIENCES, vol.19, no.1, pp.17-23, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 1
  • Publication Date: 2014
  • Journal Name: NEUROSCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.17-23
  • Çukurova University Affiliated: Yes

Abstract

Objective: To study strength-duration properties of motor and sensory axons to evaluate whether there is a change in current through the persistent sodium (Na+) channels of sensory and motor axons in peripheral nerves of epileptic patients before and after valproic acid (VPA) and carbamazepine (CBZ) treatment due to the presence of similar channels in the CNS and peripheral nervous system (PNS).