The effects of valproic acid and carbamazepine on strength-duration properties of peripheral nerve

Yerdelen D., Koc F.

NEUROSCIENCES, cilt.19, sa.1, ss.17-23, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 1
  • Basım Tarihi: 2014
  • Dergi Adı: NEUROSCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.17-23
  • Çukurova Üniversitesi Adresli: Evet

Özet

Objective: To study strength-duration properties of motor and sensory axons to evaluate whether there is a change in current through the persistent sodium (Na+) channels of sensory and motor axons in peripheral nerves of epileptic patients before and after valproic acid (VPA) and carbamazepine (CBZ) treatment due to the presence of similar channels in the CNS and peripheral nervous system (PNS).