X=Y-ZH systems as potential 1,3-dipoles .48. Enantiopure cycloadducts from oxime-nitrone-isoxazolidine cascades

DÖNDAŞ H. A. , Frederickson M., Grigg R., Markandu J., ThorntonPett M.

TETRAHEDRON, vol.53, no.42, pp.14339-14354, 1997 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 53 Issue: 42
  • Publication Date: 1997
  • Doi Number: 10.1016/s0040-4020(97)00919-8
  • Title of Journal : TETRAHEDRON
  • Page Numbers: pp.14339-14354


Enantiopure cycloadducts have been prepared in good yield via oxime-nitrone-isoxazolidine cascade reactions involving the nucleophilic opening of enantiopure epoxides with oximes followed by 1,3-dipolar cycloaddition reactions with suitable dipolarophiles. (C) 1997 Elsevier Science Ltd.