In Vitro Antifungal Susceptibility Profiles of 12 Antifungal Drugs against 55 Trichophyton schoenleinii Isolates from Tinea Capitis Favosa Patients in Iran, Turkey, and China

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Deng S., ANSARI S., Ilkit M., Rafati H., HEDAYATI M. T., Taghizadeh-Armaki M., ...Daha Fazla

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, cilt.61, sa.2, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 61 Sayı: 2
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1128/aac.01753-16
  • Dergi Adı: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Trichophyton schoenleinii, tinea capitis favosa, antifungal susceptibility testing, DERMATOPHYTE STRAINS, AGENTS, GRISEOFULVIN, FLUCONAZOLE, CHILDREN, TEHRAN, UPDATE
  • Çukurova Üniversitesi Adresli: Evet

Özet

Trichophyton schoenleinii is an anthropophilic dermatophyte mainly causing tinea favosa of the scalp in certain regions of the world, especially Africa and Asia. We investigated the in vitro susceptibilities of 55 T. schoenleinii isolates collected over the last 30 years from Iran, Turkey, and China to 12 antifungals using the CLSI broth microdilution method. Our results revealed that terbinafine and ketoconazole were the most potent antifungal agents among those tested, independently of the geographic regions where strains were isolated.