In Vitro Antifungal Susceptibility Profiles of 12 Antifungal Drugs against 55 Trichophyton schoenleinii Isolates from Tinea Capitis Favosa Patients in Iran, Turkey, and China


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Deng S. , ANSARI S., Ilkit M., Rafati H., HEDAYATI M. T. , Taghizadeh-Armaki M., ...More

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol.61, no.2, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 61 Issue: 2
  • Publication Date: 2017
  • Doi Number: 10.1128/aac.01753-16
  • Title of Journal : ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
  • Keywords: Trichophyton schoenleinii, tinea capitis favosa, antifungal susceptibility testing, DERMATOPHYTE STRAINS, AGENTS, GRISEOFULVIN, FLUCONAZOLE, CHILDREN, TEHRAN, UPDATE

Abstract

Trichophyton schoenleinii is an anthropophilic dermatophyte mainly causing tinea favosa of the scalp in certain regions of the world, especially Africa and Asia. We investigated the in vitro susceptibilities of 55 T. schoenleinii isolates collected over the last 30 years from Iran, Turkey, and China to 12 antifungals using the CLSI broth microdilution method. Our results revealed that terbinafine and ketoconazole were the most potent antifungal agents among those tested, independently of the geographic regions where strains were isolated.