Evaluation of lipid profiles in patients treated with capecitabine

SÜRMELİOĞLU N., PAYDAŞ S., KARATAŞ Y., SEYDAOĞLU G.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.47, sa.4, ss.1206-1209, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 4
  • Basım Tarihi: 2017
  • Doi Numarası: 10.3906/sag-1607-53
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.1206-1209
  • Anahtar Kelimeler: Capecitabine, triglycerides, cholesterol, INDUCED SEVERE HYPERTRIGLYCERIDEMIA, OF-THE-LITERATURE, CHEMOTHERAPY
  • Çukurova Üniversitesi Adresli: Evet

Özet

Background/aim: Capecitabine is a prodrug of 5-fluorouracil and has shown significant antitumor activity. The main adverse effects are hand-foot syndrome, diarrhea, and dermatitis. In recent years, hypertriglyceridemia has been reported in patients treated with capecitabine. Dyslipidemia is a rare but important side effect of capecitabine. The aim of this study is to examine the changes in lipid levels during capecitabine treatment and to raise awareness of pharmacovigilance.