Effects of cyclopamine and temozolomide combined treatment on miR-20a expression in glioblastoma cell line (U87)

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SENCAR L., Yilmaz D. M., Gokturk D., Polat S., COŞKUN G., ŞAKER D., ...Daha Fazla

CUKUROVA MEDICAL JOURNAL, cilt.46, sa.4, ss.1426-1432, 2021 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 46 Sayı: 4
  • Basım Tarihi: 2021
  • Doi Numarası: 10.17826/cumj.996520
  • Dergi Adı: CUKUROVA MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Academic Search Premier, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.1426-1432
  • Anahtar Kelimeler: Glioblastoma, cyclopamine, temozolomide, MiR-20a, INHIBITION, MICRORNAS, CANCER, TUMORIGENESIS, MULTIFORME, MIGRATION, HEDGEHOG
  • Çukurova Üniversitesi Adresli: Evet

Özet

Purpose: The aim of this study was to investigate miR-20a expression in glioblastoma cell line (U87) after applying cyclopamine and temozolomide (TMZ) treatment separately and in combination and to evaluate the efficiency of miR-20a in glioblastoma treatment.