MEDICINA (KAUNAS, LITHUANIA), vol.60, no.1879, pp.1-12, 2024 (SCI-Expanded)
twere accepted as having definitive sarcopenia. Results: The mean age of the 251 older adults includedin the study was 72.19 ± 6.11 years. The prevalence of sarcopenia in individuals aged 65 years andover was found to be 5.2%. Serum beta-2 microglobulin levels were statistically significantly lower insarcopenic participants compared to the control group (p = 0.002). The optimal cut-off value for serumbeta-2 microglobulin level was 2.26 mcg/mL, and values lower than this point were found to bediagnostic for sarcopenia. Regarding the cut-off value, the sensitivity was 92.31% and the specificitywas 80.77%, the positive predictive value was 70.59%, the negative predictive value was 95.45%, theYouden index was 0.731, and the area under the curve value was 0.901. Individuals who had beta-2microglobulin levels below 2.26 mcg/mL were found to have a 10.75 times higher risk of sarcopenia.Conclusions: A low serum beta-2 microglobulin level has the potential to be an important candidatebiomarker for the diagnosis of sarc