Lack of Candida africana and Candida dubliniensis in Vaginal Candida albicans Isolates in Turkey Using HWP1 Gene Polymorphisms

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GUMRAL R., SANCAK B., GÜZEL A. B., SARACLI M. A., Ilkit M.

MYCOPATHOLOGIA, cilt.172, sa.1, ss.73-76, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 172 Sayı: 1
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1007/s11046-011-9401-2
  • Dergi Adı: MYCOPATHOLOGIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.73-76
  • Anahtar Kelimeler: Candida africana, Candida albicans, Candida dubliniensis, Chlamydospore, HWP1 gene, Vaginitis, PRESUMPTIVE IDENTIFICATION, CHROMAGAR CANDIDA, RECOVERY, PREVALENCE, SPECIMENS, AGAR
  • Çukurova Üniversitesi Adresli: Evet

Özet

Candida africana differs from the common strains of C. albicans and C. dubliniensis morphologically, physiologically, genetically, and, in particular, clinically. This fungal pathogen is primarily recovered from genital specimens, especially in vaginal specimens. In this investigation, we reexamined 195 vaginal C. albicans isolates for the presence of C. africana and C. dubliniensis by using hyphal wall protein 1 (HWP1) gene polymorphisms. All study isolates were confirmed to be C. albicans, and none were verified as either C. africana or C. dubliniensis. In conclusion, the HWP1 gene polymorphisms offer a useful tool in the discrimination of C. africana, C. albicans, and C. dubliniensis. Further studies may highlight the pathogenesis and importance of this yeast in vulvovaginal candidiasis.