Antiarrhythmic Properties of Beta Blockers: Focus on Nebivolol

GÖRENEK B., Çalık A. N., KEPEZ A., Öz A., ÖZMEN Ç., SİNAN Ü. Y., ...Daha Fazla

International Journal of the Cardiovascular Academy, cilt.10, sa.2, ss.22-30, 2024 (Scopus) identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 10 Sayı: 2
  • Basım Tarihi: 2024
  • Doi Numarası: 10.4274/ijca.2024.85057
  • Dergi Adı: International Journal of the Cardiovascular Academy
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.22-30
  • Anahtar Kelimeler: anti-arrhythmic medications, arrhythmias, Beta-blockers, nebivolol
  • Çukurova Üniversitesi Adresli: Evet

Özet

Beta-blockers are commonly used medications for cardiovascular diseases. Beta-blockers are effective antiarrhythmic agents, and they are class 2 agents in the Vaughan-Williams classification. In this review, we first attempt to mention the physiology of beta-adrenergic activation in the myocardium and the role of excessive beta-adrenergic activation in arrythmiagenesis. Then, we will summarize the pharmacological properties of beta blockers and their use in specific arrhythmias. Special emphasis will be given to nebivolol, a new generation cardioselective beta-blocker with vasodilator activity, given the limited data regarding its use in arrhythmias.