X=Y-ZH systems as potential 1,3-dipoles. Part 53: Sequential nucleophilic ring opening-1,3-dipolar cycloaddition reactions of Z-oxime anions with aziridines and dipolarophiles


DÖNDAŞ H. A. , Cummins J., Grigg R., Thornton-Pett M.

TETRAHEDRON, cilt.57, sa.37, ss.7951-7964, 2001 (SCI İndekslerine Giren Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 57 Konu: 37
  • Basım Tarihi: 2001
  • Dergi Adı: TETRAHEDRON
  • Sayfa Sayıları: ss.7951-7964

Özet

Nucleophilic ring opening of aziridines involving attack of the nitrogen atom of Z-oxime anions generates nitrones which are then trapped in 1,3-dipolar cycloaddition reactions with N-methylmaleimide to afford 1: 1 mixture of endo- and exo-cycloadducts. (C) 2001 Elsevier Science Ltd. All rights reserved.