Acquired Bartter-like Syndrome presenting with Polyuria and Reversible Hypokalemia associated with Colistin Use in a Critically Ill Pediatric Patient

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Yavas D. P., EKİNCİ F., Horoz O. O., Gundeslioglu O. O., ATMIŞ B., Yildizdas D.

INDIAN JOURNAL OF CRITICAL CARE MEDICINE, cilt.25, sa.7, ss.822-824, 2021 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Sayı: 7
  • Basım Tarihi: 2021
  • Doi Numarası: 10.5005/jp-journals-10071-23898
  • Dergi Adı: INDIAN JOURNAL OF CRITICAL CARE MEDICINE
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, Veterinary Science Database
  • Sayfa Sayıları: ss.822-824
  • Anahtar Kelimeler: Bartter-like syndrome, Colistin, Hypokalemia, Pediatric, Polyuria
  • Çukurova Üniversitesi Adresli: Evet

Özet

We report a case of an acquired Bartter-like syndrome (BLS) after 3 days of treatment initiation and improved after discontinuation of colistin therapy in pediatric intensive care unit. A 2-month-old girl with spinal muscular atrophy type 1 who had respiratory distress received colistin therapy with a dose of 5 mg/kg/day for Acinetobacter baumannii complex isolation from endotracheal aspirate on the 12th day follow-up. Polyuria (6 mL/kg/hour) in the presence of normal blood pressure and hypokalemic metabolic alkalosis were developed on the 3rd day of colistin treatment. Colistin was stopped on the 4th day, and 2 days after discontinuation of colistin, polyuria improved dramatically. Her metabolic alkalosis and hypokalemia discontinued after 2 and 4 days, respectively.