Squid Ring Teeth-coated Mesh Improves Abdominal Wall Repair
PLASTIC AND RECONSTRUCTIVE SURGERY-GLOBAL OPEN, cilt.6, sa.8, 2018 (ESCI, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 6 Sayı: 8
- Basım Tarihi: 2018
- Doi Numarası: 10.1097/gox.0000000000001881
- Dergi Adı: PLASTIC AND RECONSTRUCTIVE SURGERY-GLOBAL OPEN
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
- Çukurova Üniversitesi Adresli: Evet
Özet
Background: Hernia repair is a common surgical procedure with polypropylene (PP) mesh being the standard material for correction because of its durability. However, complications such as seroma and pain are common, and repair failures still approach 15% secondary to poor tissue integration. In an effort to enhance mesh integration, we evaluated the applicability of a squid ring teeth (SRT) protein coating for soft-tissue repair in an abdominal wall defect model. SRT is a biologically derived high-strength protein with strong mechanical properties. We assessed tissue integration, strength, and biocompatibility of a SRT-coated PP mesh in a first-time pilot animal study.