Squid Ring Teeth-coated Mesh Improves Abdominal Wall Repair


Leberfinger A. N. , Hospodiuk M., Pena-Francesch A., AYAN B., Ozbolat V. , Koduru S. V. , ...Daha Fazla

PLASTIC AND RECONSTRUCTIVE SURGERY-GLOBAL OPEN, cilt.6, 2018 (ESCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 6 Konu: 8
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1097/gox.0000000000001881
  • Dergi Adı: PLASTIC AND RECONSTRUCTIVE SURGERY-GLOBAL OPEN

Özet

Background: Hernia repair is a common surgical procedure with polypropylene (PP) mesh being the standard material for correction because of its durability. However, complications such as seroma and pain are common, and repair failures still approach 15% secondary to poor tissue integration. In an effort to enhance mesh integration, we evaluated the applicability of a squid ring teeth (SRT) protein coating for soft-tissue repair in an abdominal wall defect model. SRT is a biologically derived high-strength protein with strong mechanical properties. We assessed tissue integration, strength, and biocompatibility of a SRT-coated PP mesh in a first-time pilot animal study.