Abducens nerve palsy and optic neuritis as initial manifestation in brucellosis

Goksel B. K. , Yerdelen D., Karatas M., Pelit A., Demiroglu Y. Z. , Kizilkilic O., ...Daha Fazla

SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES, cilt.38, ss.721-725, 2006 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 38 Konu: 8
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1080/00365540500466614
  • Sayfa Sayıları: ss.721-725


Cranial nerve involvement in brucellosis is rare. We present a case of brucellosis presenting with optic neuritis and abducens nerve palsy on the left side. Cerebrospinal fluid findings indicated Brucella meningitis with high protein count, low sugar level and pleocystosis. In addition, Brucella agglutination test (Wright test) was found to be 1/128 in cerebrospinal fluid. Serum agglutination test for Brucella was also positive at 1/1280. This case was diagnosed as brucellosis involving optic and abducens nerves. The patient was treated by ceftriaxone (intravenous), rifampicin (orally) and doxycycline (orally). Two months later the patient's vision acuity in the left eye had moderately improved and the patient's left abducens palsy had almost disappeared. In conclusion, cranial nerve involvement in brucellosis can have good prognosis if anti-Brucella treatment is undertaken early.