Tumor necrosis factor alpha and interleukin-1 beta levels in cerebrospinal fluid examination for the diagnosis of ventriculoperitoneal shunt-related ventriculitis

OLGUNER, Semih; BOYAR, BÜLENT; ALABAZ, Derya; ERMAN, TAHSİN; Oktay, KADİR; ARSLAN, Ali; BILGIN, Emre; OKTEN, Ali

doi:10.1007/s00381-019-04070-x

Tumor necrosis factor alpha and interleukin-1 beta levels in cerebrospinal fluid examination for the diagnosis of ventriculoperitoneal shunt-related ventriculitis

Atıf İçin Kopyala

OLGUNER S. K. , BOYAR B. , ALABAZ D., ERMAN T. , Oktay K. , ARSLAN A., et al.

CHILDS NERVOUS SYSTEM, cilt.35, ss.629-636, 2019 (SCI İndekslerine Giren Dergi)

Cilt numarası: 35 Konu: 4
Basım Tarihi: 2019
Doi Numarası: 10.1007/s00381-019-04070-x
Dergi Adı: CHILDS NERVOUS SYSTEM
Sayfa Sayısı: ss.629-636

Özet

Purpose Ventriculitis is known to develop after chronic inflammation and bacterial invasion of the ventricular surface with a recurrence of shunt infections. The aim of this study is to evaluate the diagnostic value of elevation in cerebrospinal fluid (CSF) interleukin-1 beta (IL-1 beta) and tumor necrosis factor alpha (TNF-alpha) together with CSF culture and laboratory test results in the diagnosis of ventriculoperitoneal (VP) shunt-related ventriculitis, which is known to be more problematic than conventional shunt infection.