Tumor necrosis factor alpha and interleukin-1 beta levels in cerebrospinal fluid examination for the diagnosis of ventriculoperitoneal shunt-related ventriculitis

OLGUNER S. K. , BOYAR B. , ALABAZ D. , ERMAN T. , Oktay K. , ARSLAN A., ...Daha Fazla

CHILDS NERVOUS SYSTEM, cilt.35, ss.629-636, 2019 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 35 Konu: 4
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1007/s00381-019-04070-x
  • Sayfa Sayıları: ss.629-636


Purpose Ventriculitis is known to develop after chronic inflammation and bacterial invasion of the ventricular surface with a recurrence of shunt infections. The aim of this study is to evaluate the diagnostic value of elevation in cerebrospinal fluid (CSF) interleukin-1 beta (IL-1 beta) and tumor necrosis factor alpha (TNF-alpha) together with CSF culture and laboratory test results in the diagnosis of ventriculoperitoneal (VP) shunt-related ventriculitis, which is known to be more problematic than conventional shunt infection.