Ischemia-Reperfusion Injury of Sciatic Nerve in Rats and Protective Role of Benidipine Hydrochloride

ÇAKIR T., Yucetas S. C., YAZICI G. N., SUNAR M., Arslan Y. K., KAYACI S., ...Daha Fazla

EUROPEAN JOURNAL OF THERAPEUTICS, cilt.27, sa.4, ss.286-292, 2021 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 4
  • Basım Tarihi: 2021
  • Doi Numarası: 10.5152/eurjther.2021.21031
  • Dergi Adı: EUROPEAN JOURNAL OF THERAPEUTICS
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.286-292
  • Anahtar Kelimeler: ischemia-reperfusion, sciatic nerve, benidipine hydrochloride, CALCIUM-CHANNEL BLOCKER, OXIDATIVE STRESS, LIPID-PEROXIDATION, SUPEROXIDE-DISMUTASE, THIOBARBITURIC ACID, PERIPHERAL-NERVE, NEUROPROTECTION, GLUTATHIONE, DISEASES, TISSUE
  • Çukurova Üniversitesi Adresli: Hayır

Özet

Objective: Benidipine is an antihypertansive agent which elicits vasodilatation of arteries by blocking Ca2+. The aim of this study is to investigate the neuroprotective effects of benidipine on rat sciatic nerves exposed to ischemia and reperfusion (I/R).