Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism in psoriasis in southern Turkey


Izmirli M., Sen B. B. , Rifaioglu E., GÖGEBAKAN B., ALDEMİR Ö., Sen T., et al.

ANAIS BRASILEIROS DE DERMATOLOGIA, cilt.91, ss.611-613, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 91 Konu: 5
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1590/abd1806-4841.20164766
  • Dergi Adı: ANAIS BRASILEIROS DE DERMATOLOGIA
  • Sayfa Sayısı: ss.611-613

Özet

Background: Psoriasis is a multigenic and multifactorial dermatological disease linked to cardiovascular diseases. Increased levels of homocysteine in patients with psoriasis have been demonstrated in many studies. The most frequently investigated genetic defect that plays a role in homocysteine metabolism is single point substitution (C to T) located on the 677th nucleotide of the methylenetetrahydrofolate reductase gene (MTHFR).