Intra-articular zoledronic acid in a rat osteoarthritis model: significant reduced synovitis may indicate chondroprotective effect

Cinar, B.; Ozkoc, Gurkan; BOLAT, FİLİZ; Karaeminogullari, Oguz; SEZGİN, NURZEN; Tandogan, Reha

doi:10.1007/s00167-014-2955-z

Intra-articular zoledronic acid in a rat osteoarthritis model: significant reduced synovitis may indicate chondroprotective effect

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Cinar B. M., Ozkoc G., BOLAT F., Karaeminogullari O., SEZGİN N., Tandogan R. N.

KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY, vol.23, no.5, pp.1410-1418, 2015 (SCI-Expanded)

Publication Type: Article / Article
Volume: 23 Issue: 5
Publication Date: 2015
Doi Number: 10.1007/s00167-014-2955-z
Journal Name: KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.1410-1418
Çukurova University Affiliated: No

Abstract

The aim of this experimental study was to evaluate the effect of intra-articular application of zoledronic acid (ZA) on joint cartilage and synovial tissue following induction of knee osteoarthritis (OA) in a rat model.