Nosocomial pseudomonal infections in a university hospital, Adana, Turkey

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Saltoğlu N., Akçam E., Yaman A., Kibar F., İnal A. S., Taşova Y., ...Daha Fazla

13th European Congress of Clinical Microbiology and Infectious Diseases, Nice, Fransa, 1 - 04 Nisan 2006, cilt.12, ss.2022, (Özet Bildiri)

  • Yayın Türü: Bildiri / Özet Bildiri
  • Cilt numarası: 12
  • Basıldığı Şehir: Nice
  • Basıldığı Ülke: Fransa
  • Sayfa Sayıları: ss.2022
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Çukurova Üniversitesi Adresli: Evet

Özet

Objectives: Our aim is to determine antimicrobial resistance and risk factors for nosocomial Pseudomonas infections isolated from various sites in a university hospital.

Methods: This prospective study was conducted in a university hospital with 1100-bed, between January 2004 and October 2005. Nosocomial Pseudomonas infections were investigated in hospitalised patients in ICUs and others. Hospital-acquired infections were defined by the criteria of CDC. The identification and susceptibility to antimicrobials has been performed by Vitek 2 as described by NCCLS.

Results: One hundred and seventy nosocomial Pseudomonal infections were diagnosed in 170 patients. One hundred and sixteen (68%) of the patients were male. Mean age was 43.93

years. One hundred and twelve (66%) of infections were diagnosed in ICUs. Hospitalization period was more than 20 days at 78% of the patients. Nosocomial infection types were detected as follows: Urinary tract infections 35%, pneumonia 28%, bacteraemia 19%, skin and soft tissue infection 10%,

surgical wound infection 8%. Risk factors were detected as, previously hospitalization 21.7%, previous antibiotic use 45%, mechanical ventilation 30.6%, burn 7.6%, diabetes mellitus 7%, malignancy 16.5%, COPD 6%, chronic liver disease 3.5%, collagen vascular disease 6%, chronic renal failure 2%. The results of susceptibility testing for Pseudomonas isolates are shown in the table below. The most active antimicrobial agents againts Pseudomonas spp. were carbapenems. Five percent of Pseudomonas isolates were found to be resistant to all antibiotics.

Conclusion: The high resistance rates in Pseudomonal isolates that are responsible for nosocomial infections in our hospital suggest that susceptibility pattern should be monitorised continuous and preventive procedures should be implemented. Besides, multidrug resistant Pseudomonas isolates are to take into consideration.