Usability of Achilles tendon strain elastography for the diagnosis of coronary artery disease


KOÇ A. F. , Pekoz B. C. , Donmez Y., Yasar S., Ardic M., Gorgulu F. F. , ...Daha Fazla

JOURNAL OF MEDICAL ULTRASONICS, cilt.46, sa.3, ss.343-351, 2019 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 46 Konu: 3
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1007/s10396-019-00931-9
  • Dergi Adı: JOURNAL OF MEDICAL ULTRASONICS
  • Sayfa Sayıları: ss.343-351

Özet

PurposeThere are close relationships between major coronary artery disease (CAD) risk factors and Achilles tendon thickness (AT-T) and AT strain ratio (AT-SR). Our aim was to evaluate the diagnostic importance of AT-T and AT-SR as obtained by ultrasonography (USG) and strain elastography (SE) for predicting CAD.Materials and methodsOne hundred and eighty-four patients scheduled to undergo coronary angiography were included in the study. Achilles tendon USG (B-mode and SE) and laboratory tests were performed on all patients. The patients were divided into two groups, i.e., patients with and without CAD.ResultsThe patients with CAD (72.8%) were more likely to be male, exhibited higher frequencies of diabetes mellitus (DM) and hyperlipidemia, exhibited higher levels of basal creatinine and glucose, and had higher AT-T and AT-SR values (p<0.05 for all). Age, DM, AT-T, and AT-SR independently predicted the probability of CAD in a logistic regression analysis (p<0.05 for all). Age (each year), DM (presence), AT-T (each 1mm), and AT-SR (each 0.1) increased the CAD risk by 3.4%, 2.9 times, 47.1%, and 16.0%, respectively. ROC analysis revealed AUCs of 0.665 and 0.730 for the AT-T and AT-SR values, respectively (p<0.05). The AT-SR cutoff value of 1.2 predicted the presence of CAD with 75.4% sensitivity and 72.7% specificity.ConclusionsAT-SR is a simple, inexpensive, noninvasive, reproducible, and objective parameter for the prediction of CAD. We think that AT-SR evaluation should become a part of conventional USG assessments in patients who are at a high risk of CAD.