The aim of this clinical study was to evaluate whether preoperative bone density value derived from cone-beam computed tomography (CBCT) gives predictable data about primary and secondary stability characteristics of immediately loaded dental implants under different clinical variables. A total of 77 immediately loaded implants placed in 23 patients were included the study. Bone density values of the implant recipient sites were recorded using CBCT. The maximum insertion torque values (ITVs) of the implants were recorded using a digital torque meter during surgery. Resonance frequency measurements were taken using the Osstell Mentor at 4 time points; immediately after surgery (implant stability quotient [ISQ](0)) and after 1 (ISQ(1)), 3 months (ISQ(3)), and 12 months (ISQ(12)) of loading. Data were analyzed statistically. The mean bone density and ITVs of all implants were 565 +/- 81 and 36.8 +/- 3.8 N center dot cm, respectively. The mean ISQ values were 73.6 +/- 5.8 at baseline, 71.1 +/- 6.5 after 1 month, 74.8 +/- 5.6 after 3 months, and 76.6 +/- 5.1 after 12 months of loading. Statistically significant differences were observed between ISQ(0) and ISQ(1) (P < 0.001), and ISQ(0) and ISQ(12) (P < 0.001), but not between ISQ(0) and ISQ(3) (P > 0.05). In regard to stability changes over time, statistically significant correlations were found between bone density values from CBCT and ISQ follow-up measurements, and between ITV and ISQ follow-up measurements in all examination periods. Thus, it is possible to predict primary and secondary stability characteristics of immediately loaded implants by using preoperative CBCT scan and perioperative ITV.