Akademik Veri Yönetim Sistemi
Anatolian Conference 4th on Organic Chemistry, Antalya, Türkiye, 4 - 07 Mart 2024, ss.76, (Özet Bildiri)
Since ancient times, dwarf elder, also known as Sambucus ebulus L., has been recognized as
one of the most effective medicinal herbs. Folk medicine in various regions of the world
continues to make use of it because of the numerous benefits it offers as a phytomedicine that
can be applied in a wide variety of contexts. Sub-critical water refers the water has a
temperature between 100<T<374 ̊C (Tc) and high-pressure to keep it fluid phase. The polarity
of subcritical water can be dramatically decreased with increasing temperature. Therefore this
unique and useful characteristic of it, makes subcritical water a green extraction fluid used for
a variety of organic species. A wide range of phytochemicals such as alkaloids, carbohydrates,
essential oil, flavonoids, glycosides, lignans, organic acids, polyphenolics, quinones, steroids,
and terpenes have been extracted using subcritical water. In this study, the fruit and leaves
of the Dwarf Elderberry (Sambucus Ebulus L.) plant were extracted with sub-critical water at
different temperatures (125, 140 and 160 °C) and different pressures (60 and 80 atm). The
composition of phytochemicals of each extract was determined by GC-MS. Leaf and fruits
extarcts have different phytochemical composition. Leaf extracts were rich coumarins,
chromans, fatty acid and esters, sterols, glucosides and d-tocopherol while fruit extracts was
poor in coumarins, chromans. Methyl coumarin -3-carboxylate was the most abundant
coumarin compound. 140 ̊C and 60 atm were found optimum sub-critical conditions for the
extraction of coumarins and chromans from Sambucus Ebulus L leaf (Figure 1).