Genotoxic effects of potassium bromate on human peripheral lymphocytes in vitro


Kaya F. F. , Topaktas M.

MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, vol.626, pp.48-52, 2007 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 626
  • Publication Date: 2007
  • Doi Number: 10.1016/j.mrgentox.2006.08.006
  • Title of Journal : MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
  • Page Numbers: pp.48-52

Abstract

The aim of this study was to investigate the genotoxic effects of potassium bromate, which is used as a bleaching agent in flour, on human peripheral blood lymphocytes in vitro by sister chromatid exchange (SCE), chromosomal aberrations (CA) and micronucleus (MN) tests, and also to determine whether it has any genotoxic potential for humans. Cells were treated with 400, 450, 500, 550 mu g/ml concentrations of potassium bromate for 24 and 48 h.