Prevalence and Genotypes of Helicobacter pylori in Gastric Biopsy Specimens from Patients with Gastroduodenal Pathologies in the Cukurova Region of Turkey


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NAĞIYEV T. , Yula E., Abayli B., KÖKSAL F.

JOURNAL OF CLINICAL MICROBIOLOGY, vol.47, no.12, pp.4150-4153, 2009 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 12
  • Publication Date: 2009
  • Doi Number: 10.1128/jcm.00605-09
  • Title of Journal : JOURNAL OF CLINICAL MICROBIOLOGY
  • Page Numbers: pp.4150-4153

Abstract

The effects of Helicobacter pylori genotypes on clinical prognosis in the Cukurova region of Turkey were investigated by PCR. The prevalence of type I strains carrying the s1c allele, unlike in neighboring regions and countries, was found to be significantly higher in patients with gastritis and/or gastric ulcers (P = 0.001), and that of type I strains carrying the s1a allele was found to be significantly higher in patients with duodenal ulcers (P < 0.001). The cagA gene was strongly associated with the more virulent vacA genotypes (P < 0.001).