ISRAEL JOURNAL OF VETERINARY MEDICINE, vol.69, no.2, pp.98-101, 2014 (SCI-Expanded)
Ameloblastic carcinoma (AC) is a malignant odontogenic epithelial tumor and reported rarely in domestic animals. An 8-year-old, mix breed, male dog presented to Lara Antalya Veterinary Hospital for examination of a mass on the right molar teeth of the maxilla. Oral radiographs did not show clear borders of the mass. Clinically and macroscopically, the mass was painful and had a nodular appearance and was reddish-white in color. Histopathologic examination of the mass revealed irregular shaped broad islands, sheets and nests consisting of neoplastic cells. These cells were immunopositive for carcinoembryonic antigen (CEA), pancytokeratin, Ki-67 and proliferating cell nuclear antigen (PCNA). Based on gross, histopathologic and immunohistochemical findings, the mass was diagnosed as ameloblastic carcinoma.