Antioxidant Defence Systems, Lipid Peroxidation and Acetylcholinesterase Activity of Oreochromis niloticus Exposed to Mercury and Mercury + Selenium.

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Firidin G., Kargın F., Fırat Ö., Çoğun H. Y., Fırat Ö., Firidin B., ...Daha Fazla

FRESENIUS ENVIRONMENTAL BULLETIN, cilt.24, sa.5, ss.1958-1965, 2015 (SCI-Expanded)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 24 Sayı: 5
  • Basım Tarihi: 2015
  • Dergi Adı: FRESENIUS ENVIRONMENTAL BULLETIN
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.1958-1965
  • Çukurova Üniversitesi Adresli: Evet

Özet

The objective of the present study was to evaluate the

oxidative stress potential of mercury (Hg) exposure with the

modulatory effect of selenium (Se) in the brain and kidney

tissues of Oreochromis niloticus. The fish were exposed

to 0.01 and 0.1 mg/L Hg, 0.01 mg/L Hg+0.1 mg/L Se,

and 0.1 mg/L Hg+1.0 mg/L Se, for 7 and 14 days. The activities

of total glutathione (tGSH), malondialdehyde

(MDA) and catalase (CAT), glutathione S-transferase

(GST), and acetylcholinesterase (AChE) were measured

from samples of the tissues. The results indicated that all

concentrations of Hg caused a time-dependent increase in

CAT, GST activity, whereas AChE activity and tGSH content

were decreased in brain and kidney tissues. MDA levels

in tissues of fish exposed to Hg+Se mixtures were lower

compared to those exposed to Hg only. Selenium application

in combination with mercury provided an alleviation

of the toxic effects of mercury in the investigated tissues

for biochemical parameters.

KEYWORDS: Oreochromis niloticus, mercury, selenium, antioxidant

parameters, oxidative stress