The effect of hyperventilation on strength-duration properties in diabetic polyneuropathy

Yerdelen D. , Uysal H., Koc F., Sarica Y.

CLINICAL NEUROPHYSIOLOGY, cilt.118, ss.105-110, 2007 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 118 Konu: 1
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.clinph.2006.09.017
  • Sayfa Sayıları: ss.105-110


Objective: Hyperventilation and ischaemia increase axonal excitability by changing Na+ conductance in healthy subjects. However, the changes in excitability during and after ischaemia in diabetic patients are less than in healthy controls. This is known as ischaemic resistance. In this study, we investigated the effects of hyperventilation for 20 min on strength-duration time constant (SDTC) of motor axons of the median nerve of diabetic patients with polyneuropathy to determine whether diabetics are less affected by hyperventilation, a form of resistance similar to the ischaemic resistance of diabetics.