The genotoxic effect of nicotine on chromosomes of human fetal cells: The first report described as an important study


DEMİRHAN O. , Demir C., TUNC E., INANDIKLIOGLU N., SUTCU E., SADIKOGLU N., ...Daha Fazla

INHALATION TOXICOLOGY, cilt.23, ss.829-834, 2011 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 23 Konu: 13
  • Basım Tarihi: 2011
  • Doi Numarası: 10.3109/08958378.2011.617398
  • Dergi Adı: INHALATION TOXICOLOGY
  • Sayfa Sayıları: ss.829-834

Özet

Context: Recent studies have suggested a direct contribution of nicotine - the addictive component of tobacco and tobacco smoke - to human carcinogenesis, and it remains the most common harmful substance to which pregnant women are exposed. Also, it has deleterious effects on the fetus. The sperm of smoking fathers and newborns of smoking mothers have elevated frequencies of chromosome translocations and DNA strand breaks.