The influence of cell-free supernatants (CFSs) of Leuconostoc mesenterodies subsp. cremoris, Pediococcus acidophilus, Lactococcus lactis subsp. lactis, and Streptococcus thermophilus on histamine and other biogenic amines formation by foodborne pathogens (FBP) (Salmonella parathypi A, Listeria monocytogenes, Staphylococcus aureus, and Escherichia coli) was investigated in histidine decarboxylase broth (HDB). Two different CFSs concentrations 50% and 25% and the control without CFS were prepared. Histamine production was the highest for E. coli (11163.5mg/L), followed by S. paratyphi A (10387.5 mg/L) and S. aureus (7330.6mg/L). All of the CFS of LAB strains significantly (p<.05) reduced histamine (HIS), ammonia, and other biogenic amines formation by the four strains of FBP studied. Although CFSs showed considerable inhibition effects on putrescine and agmatine, some of the CFSs showed stimulation effect on dopamine. The results of this current study showed that the functions of CFS varied depending on its concentrations and the pathogens studied.