Effect of haemodiafiltration vs conventional haemodialysis on growth and cardiovascular outcomes in children - the HDF, heart and height (3H) study


Shroff R., KARABAY BAYAZIT A. , Stefanidis C. J. , Askiti V., Azukaitis K., Canpolat N., ...Daha Fazla

BMC NEPHROLOGY, cilt.19, 2018 (SCI İndekslerine Giren Dergi) identifier identifier identifier

Özet

Background: Cardiovascular disease is prevalent in children on dialysis and accounts for almost 30% of all deaths. Randomised trials in adults suggest that haemodiafiltration (HDF) with high convection volumes is associated with reduced cardiovascular mortality compared to high-flux haemodialysis (HD); however paediatric data are scarce. We designed the haemodiafiltration, heart and height (3H) study to test the hypothesis that children on HDF have an improved cardiovascular risk profile, growth and nutritional status and quality of life, compared to those on conventional HD.