Cyclosporin Treatment in Three Children With Chronic Inflammatory Demyelinating Neuropathy

HERGUNER M., İNCECİK F., ALTUNBAŞAK Ş.

PEDIATRIC NEUROLOGY, cilt.41, sa.3, ss.223-225, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 41 Sayı: 3
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1016/j.pediatrneurol.2009.03.016
  • Dergi Adı: PEDIATRIC NEUROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.223-225
  • Çukurova Üniversitesi Adresli: Evet

Özet

Chronic inflammatory demyelinating neuropathy is an uncommon acquired poly neuropathy in children. Oral prednisolone, intravenous methyl prednisolone, and intravenous immunoglobulin are its main initial therapies. In patients resistant to these modalities, other immunosuppressants can be used. We demonstrate the efficacy of cyclosporin in three children with chronic inflammatory demyelinating neuropathy. Two of them were infants. None had adverse effects, except for hirsutism. We conclude that cyclosporin-treatment can be effective and safe in chronic inflammatory demyelinating neuropathy, when standard treatments are ineffective. Cyclosporin can also be used safely in infants. (C) 2009 by Elsevier Inc. All rights reserved.