CIRCULATING MACROPHAGE INFLAMMATORY PROTEIN-1 ALPHA (MIP1-A) AS A POTENTIAL BIOMARKER FOR THE DIAGNOSIS OF PATIENTS WITH PANCREATIC ADENOCARCINOMA


Karabulut S. , Afsar C. U. , KARABULUT M., ALIS H., BINBOGA S., OZKARA I. O. , ...More

ACTA MEDICA MEDITERRANEA, vol.32, no.4, pp.1035-1040, 2016 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 4
  • Publication Date: 2016
  • Doi Number: 10.19193/0393-6384_2016_4_128
  • Title of Journal : ACTA MEDICA MEDITERRANEA
  • Page Numbers: pp.1035-1040

Abstract

Introduction: Pancreatic cancer is the fourth leading cause of cancer-related death in the United States among both men and women. Macrophage inflammatory protein-1 alpha [MIP-1 alpha/CC-chemokine ligand 3 (CCL3)] is a small chemotactic protein detected in several kinds of tumor tissue samples and functions as a key regulator of cancer progression. This study aimed to investigate the serum MIP-1 alpha/CCL3 levels in pacreatic adenocarcinoma (PA).