Paal-Knorr Pyrrole Synthesis in Water

AKBAŞLAR D., DEMİRKOL O., Giray S.

SYNTHETIC COMMUNICATIONS, cilt.44, sa.9, ss.1323-1332, 2014 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Sayı: 9
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1080/00397911.2013.857691
  • Dergi Adı: SYNTHETIC COMMUNICATIONS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1323-1332
  • Çukurova Üniversitesi Adresli: Evet

Özet

Water was a suitable medium for Paal-Knorr pyrrole cyclocondensation. Hexa-2,5-dione was reacted with several aliphatic and aromatic primary amines, affording N-substituted 2,5-dimethyl pyrrole derivatives in good to excellent yields. An efficient, green method using water either as environmentally friendly solvent or catalyst was presented.