Congenital cutaneous kaposiform hemangioendothelioma in a newborn calf

Epikmen E. T. , Aydoğan A. , Avcı H., Birincioğlu S. S.

Macedonian Veterinary Review, cilt.43, ss.1-4, 2020 (Hakemli Üniversite Dergisi)

  • Cilt numarası: 43 Konu: 2
  • Basım Tarihi: 2020
  • Dergi Adı: Macedonian Veterinary Review
  • Sayfa Sayıları: ss.1-4

Özet

A one-day-old female Holstein calf was presented with subcutaneous masses spread over the whole body. Macroscopically,

the masses were firm in touch, greyish-white in colour, 0.5-2 cm in diameter range. Histopathological examination

confirmed the cutaneous Kaposiform hemangioendothelioma (KHE). Microscopic examination of the tumor revealed sheets

of spindled endothelial cells forming vascular slits. Immunohistochemically, the tumor cells and capillaries gave strongly

positive reaction for CD31 while vimentin, alpha smooth muscle actin and cytokeratin AE1/AE3 were negative. In this case,

macroscopical, detailed histhopathological and immunohistochemical findings of congenital KHE reported firstly in a newborn calf.