Congenital cutaneous kaposiform hemangioendothelioma in a newborn calf


Epikmen E. T., Aydoğan A., Avcı H., Birincioğlu S. S.

Macedonian Veterinary Review, vol.43, no.2, pp.1-4, 2020 (Scopus)

  • Publication Type: Article / Case Report
  • Volume: 43 Issue: 2
  • Publication Date: 2020
  • Journal Name: Macedonian Veterinary Review
  • Journal Indexes: Scopus, Academic Search Premier, CAB Abstracts, EMBASE, Veterinary Science Database, Directory of Open Access Journals
  • Page Numbers: pp.1-4
  • Çukurova University Affiliated: Yes

Abstract

A one-day-old female Holstein calf was presented with subcutaneous masses spread over the whole body. Macroscopically,

the masses were firm in touch, greyish-white in colour, 0.5-2 cm in diameter range. Histopathological examination

confirmed the cutaneous Kaposiform hemangioendothelioma (KHE). Microscopic examination of the tumor revealed sheets

of spindled endothelial cells forming vascular slits. Immunohistochemically, the tumor cells and capillaries gave strongly

positive reaction for CD31 while vimentin, alpha smooth muscle actin and cytokeratin AE1/AE3 were negative. In this case,

macroscopical, detailed histhopathological and immunohistochemical findings of congenital KHE reported firstly in a newborn calf.