Diagnosis and treatment of solid pseudopapillary tumor of the pancreas: A single center’s experience


SARITAŞ A. G., Gul M. O., Ulku A., Gumus S., Aydin I., Akcam A. T.

Northern Clinics of Istanbul, vol.11, no.4, pp.328-335, 2024 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 11 Issue: 4
  • Publication Date: 2024
  • Doi Number: 10.14744/nci.2023.36776
  • Journal Name: Northern Clinics of Istanbul
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, Central & Eastern European Academic Source (CEEAS), Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.328-335
  • Keywords: Pancreas, pancreatic resection, pancreatic tumor, solid pseudopapillary tumor
  • Çukurova University Affiliated: Yes

Abstract

OBJECTIVE: The present study reviews the records of patients with solid pseudopapillary pancreas neoplasm (SPT). METHODS: A total of 13 patients diagnosed with SPT were included in the study. The criteria for SPT in the pathology speci-mens were the presence of cells with an oval round orthochromatic nucleus, with a thin chromatin structure and no nucleolus distinction, lined around a fibrovascular papilla in cystic areas. RESULTS: The study included 11 female and two male patients, with a mean age of 33.07 (range: 16–73) years. All operated patients underwent open surgery, with five undergoing a subtotal pancreatectomy and splenectomy; one a distal pancreate-ctomy and splenectomy; four a spleen-preserving distal pancreatectomy; and one a pancreaticoduodenectomy. None of the operated patients developed recurrence during the long-term follow-up. The mean follow-up time of operable patients was 69.18 (range: 22–97) months, and none had metastasis at follow-up. The mean follow-up time for the malignant SPT patients was 2.75 (1.5–4) months. CONCLUSION: SPTs are rare pancreatic tumors encountered more frequently today due to advances in imaging methods and have a low potential of recurrence and a good prognosis.