Sequential 1,3-dipolar cycloaddition-Pictet-Spengler reactions. A versatile tactical combination

DÖNDAŞ H. A., Duraisingham J., Grigg R., MacLachlan W., MacPherson D., Thornton-Pett M., ...Daha Fazla

TETRAHEDRON, cilt.56, sa.24, ss.4063-4070, 2000 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 56 Sayı: 24
  • Basım Tarihi: 2000
  • Doi Numarası: 10.1016/s0040-4020(00)00320-3
  • Dergi Adı: TETRAHEDRON
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.4063-4070
  • Anahtar Kelimeler: metallo-azomethine ylides, Ag catalysis, cycloaddition, Pictet-Spengler reactions, ALPHA-AMINO-ACIDS, X=Y-ZH SYSTEMS, POTENTIAL 1,3-DIPOLES, AZOMETHINE YLIDES, CONDENSATION, IMINES
  • Çukurova Üniversitesi Adresli: Hayır

Özet

The combination of thermal or Ag(I) catalysed imine-->azomethine ylide-->cycloaddition cascades with a subsequent Pictet-Spengler reaction allows the assembly of polyfunctional N-heterocycles, via formation of 4 bonds and 2 rings, in good yield. (C) 2000 Elsevier Science Ltd. All rights reserved.