Advances in 1,3,5-triazepines chemistry

Elattar K. M. , DOĞRU MERT B. , Abozeid M. A. , El-Mekabaty A.

RSC ADVANCES, vol.6, no.43, pp.37286-37307, 2016 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Review
  • Volume: 6 Issue: 43
  • Publication Date: 2016
  • Doi Number: 10.1039/c6ra00590j
  • Title of Journal : RSC ADVANCES
  • Page Numbers: pp.37286-37307


This review describes a literature survey of 1,3,5-triazepines. The investigated heterocycles were the monocyclic and fused 1,3,5-triazepines. The different sections of the paper cover: theoretical methods, spectroscopy aspects, thermodynamic aspects, synthesis and reactions of the monocyclic and fused heterocycles incorporated into the 1,3,5-triazepine moiety. The biological evaluation of the target compounds are also described as well as their synthetic applications. The reaction mechanisms are discussed.