The toxicity and teratogenicity of gibberellic acid (GA(3)) based on the frog embryo teratogenesis assay-Xenopus (FETAX)

Boga A., Binokay S., Sertdemir Y.

TURKISH JOURNAL OF BIOLOGY, vol.33, no.3, pp.181-188, 2009 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 3
  • Publication Date: 2009
  • Doi Number: 10.3906/biy-0807-30
  • Journal Name: TURKISH JOURNAL OF BIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.181-188
  • Çukurova University Affiliated: Yes

Abstract

This study investigated the developmental toxicity of a plant growth regulator (a type of pesticide) using the frog embryo teratogenesis assay-Xenopus (FETAX). Xenopus laevis embryos were exposed to 11 different concentrations of gibberellic acid (GA(3)), from stage 8 to 11, for 96 h under static renewal test conditions. The median lethal concentration (LC50), malformation (EC50), non-observed adverse effect concentration (NOAEC), and lowest observed adverse effect concentration (LOAEC) were calculated.