The toxicity and teratogenicity of gibberellic acid (GA(3)) based on the frog embryo teratogenesis assay-Xenopus (FETAX)


Boga A., Binokay S., Sertdemir Y.

TURKISH JOURNAL OF BIOLOGY, cilt.33, ss.181-188, 2009 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 33 Konu: 3
  • Basım Tarihi: 2009
  • Doi Numarası: 10.3906/biy-0807-30
  • Dergi Adı: TURKISH JOURNAL OF BIOLOGY
  • Sayfa Sayıları: ss.181-188

Özet

This study investigated the developmental toxicity of a plant growth regulator (a type of pesticide) using the frog embryo teratogenesis assay-Xenopus (FETAX). Xenopus laevis embryos were exposed to 11 different concentrations of gibberellic acid (GA(3)), from stage 8 to 11, for 96 h under static renewal test conditions. The median lethal concentration (LC50), malformation (EC50), non-observed adverse effect concentration (NOAEC), and lowest observed adverse effect concentration (LOAEC) were calculated.