Determination of correlation between principal genotypes of Helicobacter pylori according to cagPAI components and vacA genotypes and clinical out come in patients suffering from active chronic gastritis and gastric adenocarcinoma from Iran and Turkey

BAHADORI A., SOMI M. H., DORAN F., EFTEKHARSADAT A., KIZILYILDRIM S., ESMAEILLOU M., ...More

BIOMEDICAL RESEARCH-INDIA, vol.28, no.4, pp.1743-1748, 2017 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 4
  • Publication Date: 2017
  • Journal Name: BIOMEDICAL RESEARCH-INDIA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Chemical Abstracts Core
  • Page Numbers: pp.1743-1748
  • Çukurova University Affiliated: Yes

Abstract

Objective(s): Helicobacter pylori are gastric infectious agents that colonizes majority of the world's population. Genetic diversity among the virulence factors of bacterium like cytotoxin associated gene Pathogenicity Island (cagPAI) and vacuolating cytotoxinA (vacA) could have a modifying result on the pathogenic potential of the infecting strain. This study aimed to analyse which genes can be recommended as doubtless related virulence factors for H. pylori associated active chronic gastritis and stomach adenocarcinoma in Iranian and Turkish population.