Randomized trial of sertraline versus venlafaxine XR in major depression: Efficacy and discontinuation symptoms


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Sir A., D'Souza R., Uguz S. , George T., Vahip S., Hopwood M., ...More

JOURNAL OF CLINICAL PSYCHIATRY, vol.66, no.10, pp.1312-1320, 2005 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 66 Issue: 10
  • Publication Date: 2005
  • Doi Number: 10.4088/jcp.v66n1015
  • Title of Journal : JOURNAL OF CLINICAL PSYCHIATRY
  • Page Numbers: pp.1312-1320

Abstract

Background: The comparative efficacy of selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepmephrine reuptake inhibitors (SNRIs) was recently debated. Meta-analyses, based mainly on fluoxetine comparator data, suggest that the SNRI venlafaxine has superior efficacy to SSRIs in treatment of major depression.