Randomized trial of sertraline versus venlafaxine XR in major depression: Efficacy and discontinuation symptoms


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Sir A., D'Souza R., Uguz S., George T., Vahip S., Hopwood M., ...More

JOURNAL OF CLINICAL PSYCHIATRY, vol.66, no.10, pp.1312-1320, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 66 Issue: 10
  • Publication Date: 2005
  • Doi Number: 10.4088/jcp.v66n1015
  • Journal Name: JOURNAL OF CLINICAL PSYCHIATRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Page Numbers: pp.1312-1320
  • Çukurova University Affiliated: Yes

Abstract

Background: The comparative efficacy of selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepmephrine reuptake inhibitors (SNRIs) was recently debated. Meta-analyses, based mainly on fluoxetine comparator data, suggest that the SNRI venlafaxine has superior efficacy to SSRIs in treatment of major depression.