Life-threatening Paraneoplastic Syndrome in a Child With Sarcoma of the Liver Cured by Emergency Resection

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Atıf İçin Kopyala

Fricchione M. J., Glenn N., Follmer R., Kent P. M.

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, cilt.35, sa.2, ss.153-155, 2013 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 35 Sayı: 2
• Basım Tarihi: 2013
• Doi Numarası: 10.1097/mph.0b013e318266bf55
• Dergi Adı: JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.153-155
• Çukurova Üniversitesi Adresli: Hayır

Özet

We believe this to be the first case of life-threatening paraneoplastic syndrome (PNS) in a child with undifferentiated embryonal sarcoma of the liver (UESL). We report a case of a 9-year-old child with UESL believed to be unresectable at presentation, who experienced life-threatening, refractory long QTc syndrome, Torsades de pointes, fevers of unknown origin, and secretory diarrhea necessitating emergency surgery. After failure of intravenous immunoglobulin and high-dose steroids to control PNS and despite pancytopenia from chemotherapy, very aggressive surgical resection was life saving and led to rapid resolution of PNS.