MALDI-TOF MS characterisation, genetic diversity and antifungal susceptibility of Trichosporon species from Iranian clinical samples.

Ahangarkani F., Ilkit M. M., Vaseghi N., Zahedi N., Zomorodian K., Khodavaisy S., ...Daha Fazla

Mycoses, cilt.64, ss.918-925, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 64
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1111/myc.13306
  • Dergi Adı: Mycoses
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.918-925
  • Anahtar Kelimeler: amplified fragment length polymorphism, Iran, matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry, susceptibility, Trichosporon, MOLECULAR-IDENTIFICATION, ASAHII, INFECTIONS, SPP.
  • Çukurova Üniversitesi Adresli: Evet

Özet

Background: Trichosporonosis is an emerging fungal infection caused by Trichosporon species, a genus of yeast-like fungi, which are frequently encountered in human infections ranging from mild cutaneous lesions to fungemia in immunocompromised patients. The incidence of trichosporonosis has increased in recent years, owing to higher numbers of individuals at risk for this infection. Although amphotericin B, posaconazole and isavuconazole are generally effective against Trichosporon species, some isolates may have variable susceptibility to these antifungals.