Deferasirox-induced cytogenetic responses

Arslan M., İLA H. B.

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, cilt.39, sa.2, ss.787-793, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 39 Sayı: 2
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1016/j.etap.2015.02.001
  • Dergi Adı: ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.787-793
  • Çukurova Üniversitesi Adresli: Evet

Özet

Deferasirox (commercially formulated as Exjade (R)) is one of the effective iron chelators used in treatment of iron overload diseases. In this study the effect of this substance for chromosome aberration, sister chromatid exchange and mitotic index was studied by in vitro (by using human peripheral lymphocytes) and in vivo (by using rat) analysis.