REVISTA BRASILEIRA DE ANESTESIOLOGIA, vol.68, no.6, pp.605-612, 2018 (SCI-Expanded)
Background: A single dose injection or continuous infusion of local anesthetics into the joint space is considered to be a well-defined analgesia technique. The aim of this study was to investigate the chondrotoxic and apoptotic effects of single-dose intra-articular injection of levobupivacaine and bupivacaine on rabbit knee joint tissues.