The chondrotoxic and apoptotic effects of levobupivacaine and bupivacaine on the rabbit knee joint

Cevik, Osman; Gergin, Ozlem; YILDIZ, KARAMEHMET; BAYRAM , ADNAN; CANÖZ, ÖZLEM; HALICI, MEHMET; BARAN, MÜNEVVER; Yay, Arzu; POLAT, SAİT

doi:10.1016/j.bjan.2018.06.013

The chondrotoxic and apoptotic effects of levobupivacaine and bupivacaine on the rabbit knee joint

Copy For Citation

Cevik O., Gergin O. O., YILDIZ K., BAYRAM A., CANÖZ Ö., HALICI M., ...More

REVISTA BRASILEIRA DE ANESTESIOLOGIA, vol.68, no.6, pp.605-612, 2018 (SCI-Expanded)

Publication Type: Article / Article
Volume: 68 Issue: 6
Publication Date: 2018
Doi Number: 10.1016/j.bjan.2018.06.013
Journal Name: REVISTA BRASILEIRA DE ANESTESIOLOGIA
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.605-612
Çukurova University Affiliated: Yes

Abstract

Background: A single dose injection or continuous infusion of local anesthetics into the joint space is considered to be a well-defined analgesia technique. The aim of this study was to investigate the chondrotoxic and apoptotic effects of single-dose intra-articular injection of levobupivacaine and bupivacaine on rabbit knee joint tissues.