The chondrotoxic and apoptotic effects of levobupivacaine and bupivacaine on the rabbit knee joint


Cevik O., Gergin O. O. , YILDIZ K., BAYRAM A., CANÖZ Ö., HALICI M., ...More

REVISTA BRASILEIRA DE ANESTESIOLOGIA, vol.68, no.6, pp.605-612, 2018 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 68 Issue: 6
  • Publication Date: 2018
  • Doi Number: 10.1016/j.bjan.2018.06.013
  • Title of Journal : REVISTA BRASILEIRA DE ANESTESIOLOGIA
  • Page Numbers: pp.605-612

Abstract

Background: A single dose injection or continuous infusion of local anesthetics into the joint space is considered to be a well-defined analgesia technique. The aim of this study was to investigate the chondrotoxic and apoptotic effects of single-dose intra-articular injection of levobupivacaine and bupivacaine on rabbit knee joint tissues.